Thank you for your interest in the DINE-CD research study. This study is sponsored by Crohn’s and Colitis Foundation and the Patient-Centered Outcomes Research Institute (PCORI).

The goal of the DINE-CD study is to compare the efficacy of two different dietary strategies to reduce symptoms and intestinal inflammation of Crohn’s disease. The two diets that will be studied are the Mediterranean style diet and the Specific Carbohydrate Diet.

Adults with Crohn’s disease that is currently causing mild to moderately severe symptoms and who have elevated markers of inflammation will be eligible to participate in the study. Participants will be randomly assigned to follow one of the two diets for 12 weeks. For the first 6 weeks, participants will be provided with all of their food. For the last 6 weeks of the study, participants will be asked to follow the diet on their own, although they will have the option to buy some or all of their meals from the same vendor who will be providing the food during the first six weeks. Participants will complete 3 study visits at one of our study sites located throughout the United States.

For more information or for information about locations where you can meet with a physician to be screened for eligibility, please see our page:

Please note: you must meet with a physician at one of our participating sites and meet all eligibility criteria to enroll in this study.

For general questions please e-mail the coordinating center at the University of Pennsylvania: